Can Risk Stratification Tools be Utilized to Safely Discharge Low-Risk Febrile Neutropenic Patients from the Emergency Department?

Statement reviewed and approved by AAEM Board of Directors. (11/10/2021)

Summary Recommendation:

  1. Febrile Neutropenia risk stratifications tools, such as the Multinational Association of Supportive Care in
    Cancer (MASCC) and Clinical Index of Stable Febrile Neutropenia (CISNE) scores, are supported by the
    existing literature and may be included as part of the decision-making process when considering adult
    patient disposition. There is no widely accepted risk stratification tool for use in the pediatric population.
  2. Further research is needed before biomarkers can be included in febrile neutropenia risk stratification
    decisions.
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References and Literature Grading (PDF)